Properties
Description
ARQ 197, soluble in DMSO and insoluble in ethanol and water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis.
Molecular Formula
C23H19N3O2
Solubility
DMSO: 69 mg/mL (186.77 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
ARQ 197 is employed to inhibit c-MET, a key receptor in various signaling pathways, potentially offering therapeutic benefits in cancer research.
