Properties
Description
INCB28060, soluble in DMSO and insoluble in ethanol and water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis. It targets c-Met.
Molecular Formula
C23H17FN6O
Solubility
DMSO: 2 mg/mL (4.84 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
INCB28060 acts as a c-MET inhibitor, relevant in studies aiming to block MET-mediated oncogenic pathways.
