Properties
Description
JNJ-38877605, soluble in DMSO and insoluble in ethanol and water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis.
Molecular Formula
C19H13F2N7
Solubility
DMSO: 33 mg/mL (87.45 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
JNJ-38877605 is involved in inhibiting c-MET, useful in cancer research focusing on receptor tyrosine kinases as drug targets.
