c-MET inhibitor JNJ-38877618, Purity ≥98%

Synonym: 943540-74-7; c-MET inhibitor; JNJ38877618; JNJ 38877618

CAS Number: 943540-74-7
Compound CID: 57654476

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

JNJ-38877618, soluble in DMSO and ethanol and insoluble in water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis.

Molecular Weight

374.355

Molecular Formula

C₂₀H₁₂F₂N₆

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 9 mg/mL (24.04 mM); Water: Insoluble; Ethanol: 2 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

JNJ-38877618 is another c-MET inhibitor employed in investigating therapeutic approaches against cancer involving MET dysregulation.