Properties
Description
PF-04217903, soluble in DMSO and insoluble in ethanol and water, inhibits the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), interfering with pathways leading to cell growth and metastasis. It targets c-Met (A549 cells).
Molecular Formula
C19H16N8O
Targets
c-Met (A549 cells): 4.8 nM
Solubility
DMSO: 5 mg/mL (13.42 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PF-04217903 serves in research as a c-MET inhibitor, advancing studies on MET-driven cancer therapies.
