c-Ret inhibitor cis-Pralsetinib, Purity ≥98%

Synonym: 2097132-94-8; Pralsetinib; BLU-667; Pralsetinib free base; Gavreto; Blu667; trans-Pralsetinib; c-Ret inhibitor

CAS Number: 2097132-93-7
Compound CID: 129073603

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

cis-Pralsetinib primarily acts by blocking the ATP-binding site of the kinase domain of the RET protein, thereby inhibiting its autophosphorylation.

Molecular Weight

533.6

Molecular Formula

C₂₇H₃₂FN₉O₂

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

cis-Pralsetinib can be used to study its selective inhibition of RET kinase in oncology research.