Calcium channel inhibitor CK-1827452, Purity ≥98%

Synonym: 873697-71-3; Calcium channel inhibitor; CK1827452; Omecamtiv Mecarbil

MDL: MFCD18633260
CAS Number: 873697-71-3
Compound CID: 11689883

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CK-1827452, soluble in DMSO and ethanol and insoluble in water, blocks the entry of calcium into cells, particularly in the heart and blood vessels. It targets Myosin ATPase.

Molecular Weight

401.43

Molecular Formula

C₂₀H₂₄FN₅O₃

Targets

Myosin ATPase

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 73 mg/mL (181.84 mM); Water: Insoluble; Ethanol: 5 mg/mL (12.45 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

CK-1827452 is a calcium channel inhibitor explored in studies aimed at its potential to enhance cardiac contractility and treat heart failure.