Capecitabine Analysis Service

Empowering Precision with Capecitabine Analysis

Capecitabine is an oral fluoropyrimidine nucleoside metabolic inhibitor anticancer agent. Capecitabine is broken down in the body to produce substances that interfere with the production of DNA, RNA, and proteins, thereby affecting the growth of cancer cells and other fast-growing cells. Thus, capecitabine is a useful Pharmaceutical. CD BioGlyco provides comprehensive identification services for capecitabine and its metabolites. Moreover, we offer fundamental analytical services.

Fig.1 The structural formula of capecitabine. (CD BioGlyco)

• Fundamental analysis
  
  • Solubility test: We test the solubility of capecitabine in various solvents such as methanol, acetonitrile, ethanol, and water.
  • Specific rotation test: Our researchers accurately weigh a small number of samples dissolving in methanol and measure their specific rotation after quantitative dilution.
  • Identification: We compare the plots of samples and standards by high-performance liquid chromatography (HPLC) and infrared spectroscopy. Their liquid phase retention times and spectral characteristic peaks are analyzed one by one. Combining HPLC and mass spectrometry (MS), we perform high-quality analysis of capecitabine and impurities in the samples. Moreover, we provide capecitabine metabolite and impurity characterization services.
  • Others: We provide moisture testing in samples, analysis of residual solvents, and analysis of heavy metals in incandescent residues.
• Capecitabine-loaded vehicle analysis
  
  • We provide characterization services for capecitabine binding vehicles (e.g. microsphere, copolymer). We measure their in vitro drug release efficiency, cytotoxicity, etc.
• Pharmacokinetic analysis
  
  • Our researchers provide physiological pharmacokinetic (PBPK) modeling services for capecitabine and its metabolites, with detailed analysis of pharmacokinetics in animal model tumors and plasma. Moreover, we analyze the expression of the protein in the cells before and after drug administration.

Fig.2 Schematic diagram of capecitabine analysis service. (CD BioGlyco)

Publication Data

Advantages

• CD BioGlyco has a professional research team and advanced analysis system to provide clients with a variety of Pharmaceutical and Biological analyses.
• CD BioGlyco provides accurate qualitative and quantitative analysis services in capecitabine and its metabolites analysis.
• All analytical data and diagrams are professionally analyzed by our technicians.

Depending on the pharmaceutical characteristics, CD BioGlyco provides a complete analytical solution for our clients. Our serious service attitude and thoughtful service have been praised by clients around the world. If you are interested in the capecitabine analysis service, please feel free to contact us.