Properties
Description
U-104, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting carbonic anhydrase. The molecular weight of the compound is 309.32, and its molecular formula is C13H12FN3O3S. It targets the CAI, CAII, CAIX and CAXII.
Molecular Formula
C13H12FN3O3S
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 60 mg/mL (193.96 mM); Water: insoluble; Ethanol: insoluble; In vivo: 30% PEG400 + 0.5% Tween80 + 5% propylene glycol,28 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
U-104 displays the significant potential to act as an effective ureido-sulfonamide inhibitor of carbonic anhydrase IX (CAIX).