Properties
Description
D4476, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits Casein kinase activity. It targets ALK5, CK1, and CK1δ.
Molecular Formula
C23H18N4O3
Targets
ALK5: 500 nM; CK1: 200 nM; CK1δ: 300 nM
Solubility
DMSO: 71 mg/mL (178.2 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
D4476 is a Casein kinase inhibitor used for studying its effects on Wnt signaling and cancer.