Properties
Description
PF 670462, soluble in DMSO, water and ethanol, is a potent compound that inhibits Casein kinase activity. It targets CKIδ, EGFR, and SAPK2A/p38.
Molecular Formula
C19H20FN5.2HCl
Targets
CKIδ: 14 nM; EGFR: 150 nM; SAPK2A/p38: 190 nM
Solubility
DMSO: 80 mg/mL (194.97 mM); Water: 80 mg/mL (194.97 mM); Ethanol: 27 mg/mL (65.79 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PF 670462 is studied for its role in inhibiting casein kinase 1, affecting circadian rhythm modulation.