Caspase inhibitor Belnacasan, Purity ≥98%

Cat. No.: X23-10-ZQ056

Caspase inhibitor Belnacasan, Purity ≥98%

Synonym: 273404-37-8; BELNACASAN; VX-765; Belnacasan (VX-765); VX765; Belnacasan [USAN]; (S)-1-((S)-2-(4-Amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide; Caspase inhibitor

  • MDL: MFCD11100350
  • CAS Number: 273404-37-8
  • Compound CID: 11398092
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
Belnacasan, soluble in warmed DMSO and warmed ethanol and insoluble in water, inhibits the activity of caspases, thereby preventing apoptosis. It targets Caspase-4 and Caspase-1.
Molecular Weight
509
Molecular Formula
C24H33ClN4O6
Targets
Caspase-4: <0.6 nM (Ki); Caspase-1: 0.8 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 87 mg/mL (170.92 mM); Water: Insoluble; Warmed ethanol: 87 mg/mL (170.92 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Belnacasan (VX-765) can be used to research the inhibition of interleukin-1尾 converting enzyme (caspase-1) and its effects on inflammatory diseases.
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