Properties
Description
Q-VD-OPh hydrate, soluble in DMSO and ethanol and insoluble in water, inhibits the activity of caspases, thereby preventing apoptosis. It targets Caspase-1, Caspase-3, Caspase-8, and Caspase-9.
Molecular Formula
C26H25F2N3O6
Targets
Caspase-1: 25-400 nM; Caspase-3: 25-400 nM; Caspase-8: 25-400 nM; Caspase-9: 25-400 nM
Solubility
DMSO: 94 mg/mL (183.06 mM); Water: Insoluble; Ethanol: 94 mg/mL (183.06 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Q-VD-OPh hydrate can be used as a broad-spectrum caspase inhibitor in apoptosis research.