Caspase inhibitor Z-VAD-FMK, Purity ≥98%

Synonym: 187389-52-2; Z-VAD(OMe)-FMK; Z-Val-Ala-Asp(OMe)-FMK; Pan-caspase inhibitor; 5-Bromo-2 -deoxyuridine; Methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-phenylmethoxycarbonylamino-butanoyl]amino]propanoyl]amino]-4-oxo-pentanoate; Caspase inhibitor

MDL: MFCD02684037
CAS Number: 187389-52-2
Compound CID: 5497174

Product Size

1 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Z-VAD-FMK, soluble in DMSO and insoluble in ethanol and water, inhibits the activity of caspases, thereby preventing apoptosis. It targets pan-caspase (THP.1, Jurkat T-cells).

Molecular Weight

467.49

Molecular Formula

C₂₂H₃₀FN₃O₇

Targets

Pan-caspase (THP.1, Jurkat T-cells): 0.0015-5.8 mM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 80 mg/mL (171.12 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Z-VAD-FMK can be used to broadly inhibit caspases in research focused on apoptosis and necroptosis pathways.