Properties
Description
Z-VAD-FMK, soluble in DMSO and insoluble in ethanol and water, inhibits the activity of caspases, thereby preventing apoptosis. It targets pan-caspase (THP.1, Jurkat T-cells).
Molecular Formula
C22H30FN3O7
Targets
Pan-caspase (THP.1, Jurkat T-cells): 0.0015-5.8 mM
Solubility
DMSO: 80 mg/mL (171.12 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Z-VAD-FMK can be used to broadly inhibit caspases in research focused on apoptosis and necroptosis pathways.