Properties
Description
Cathepsin inhibitor 1, soluble in DMSO and ethanol and insoluble in water, obstructs cysteine proteases, enzymes implicated in numerous diseases due to their role in protein degradation. It targets cathepsin K, cathepsin L, cathepsin L2, cathepsin S, and Cathepsin S.
Molecular Formula
C20H24ClN5O2
Targets
Cathepsin K: 5.5 (pIC50); Cathepsin L: 7.9 (pIC50); Cathepsin L2: 6.7(pIC50); Cathepsin S: 6 (pIC50); Cathepsin S: 5.2 (pIC50)
Solubility
DMSO: 70 mg/mL (174.17 mM); Water: Insoluble; Ethanol: 44 mg/mL (109.48 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Cathepsin inhibitor 1 focuses on inhibiting cathepsins, cysteine proteases that are crucial in protein degradation, explored in cancer and neurodegenerative disease studies.
