Properties
Description
CCG 50014, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets RGS16, RGS19, RGS4, and RGS8.
Molecular Formula
C16H13FN2O2S
Targets
RGS16: 3.5 μM; RGS19: 0.12 μM; RGS4: 30 nM; RGS8: 11 μM
Solubility
DMSO: 61 mg/mL (192.82 mM); Water: insoluble; Ethanol: insoluble
Applications
CCG 50014 can be used for its ability to inhibit several other RGS proteins, including RGS8, -16, and -19.