Properties
Description
CCG 50014, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets RGS16, RGS19, RGS4, and RGS8.
Molecular Formula
C16H13FN2O2S
Targets
RGS16: 3.5 μM; RGS19: 0.12 μM; RGS4: 30 nM; RGS8: 11 μM
Solubility
DMSO: 61 mg/mL (192.82 mM); Water: insoluble; Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
CCG 50014 can be used for its ability to inhibit several other RGS proteins, including RGS8, -16, and -19.
Storage
Store at -20°C, and keep desiccated.