Properties
Description
Maraviroc, soluble in DMSO and ethanol and insoluble in water, is an active small molecule compound that mediates the CCR signaling pathway. It targets MIP1α, RANTES, and MIP1β.
Molecular Formula
C29H41F2N5O
Targets
MIP1α: 3.3 nM; RANTES: 5.2 nM; MIP1β: 7.2 nM
Solubility
DMSO: 91 mg/mL (177.15 mM); Water: Insoluble; Ethanol: 91 mg/mL (177.15 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Maraviroc can be used to investigate its role as a CCR5 antagonist in HIV therapy.