Aplaviroc specifically binds to chemokine receptors. This binding blocks the receptors and prevents the corresponding chemokines from exerting their effects on immune cells, leading to reduced chemotaxis and cell activation.
Molecular Weight
577.711
Molecular Formula
C33H43N3O6
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
Aplaviroc can be applied in the study of its efficacy as a CCR5 antagonist in HIV-1 infection.
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