Properties
Description
SB297006, soluble in DMSO and ethanol and insoluble in water, specifically binds to chemokine receptors. This binding blocks the receptors and prevents the corresponding chemokines from exerting their effects on immune cells, leading to reduced chemotaxis and cell activation.
Molecular Formula
C18H18N2O5
Solubility
DMSO: 58 mg/mL (169.41 mM); Water: Insoluble; Ethanol: 17 mg/mL (49.65 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
SB297006 is investigated for its role as a chemokine receptor inhibitor, offering insights into therapeutic strategies for inflammatory diseases.