Properties
Description
Alsterpaullone is an CDK kinase inhibitor that disrupts cell division processes. It targets Cdk1/cyclin B, CDK2/Cyc E, cdk2/cyclin A, and CDK5/p35.
Molecular Formula
C16H11N3O3
Targets
Cdk1/cyclin B: 35 nM; CDK2/Cyc E: 200 nM; cdk2/cyclin A: 15 nM; CDK5/p35: 40 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Alsterpaullone can be used to explore its broad kinase inhibition, including CDKs, and its effects on cell cycle and apoptosis.