Properties
Description
Alsterpaullone is an CDK kinase inhibitor that disrupts cell division processes. It targets Cdk1/cyclin B, CDK2/Cyc E, cdk2/cyclin A, and CDK5/p35.
Molecular Formula
C16H11N3O3
Targets
Cdk1/cyclin B: 35 nM; CDK2/Cyc E: 200 nM; cdk2/cyclin A: 15 nM; CDK5/p35: 40 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
Alsterpaullone can be used to explore its broad kinase inhibition, including CDKs, and its effects on cell cycle and apoptosis.