CDK inhibitor AMG-925, Purity ≥98%

Synonym: 1401033-86-0; AMG925; AMG 925; CDK inhibitor

CAS Number: 1401033-86-0
Compound CID: 60202647

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

MSDS

Properties

Description

AMG-925, soluble in DMSO and water and insoluble in ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1, CDK4, and FLT3.

Molecular Weight

471.55

Molecular Formula

C₂₆H₂₉N₇O₂

Targets

CDK1: 2.22 μM; CDK4: 3 nM; FLT3: 1 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 0.01 mg/mL (0.02 mM); Water: <1 mg/mL; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

AMG-925 can be used to study the dual inhibition of FLT3 and CDK4/6 in cancer cells.