CDK inhibitor AT7519 HCl, Purity ≥98%

Synonym: 902135-91-5; AT 7519; AT-7519; CDK inhibitor

CAS Number: 902135-91-5
Compound CID: 25033099

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AT7519 HCl, soluble in warmed DMSO, warmed water and warmed ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK2/CyclinA, CDK5/p35, AuroraA, and c-Abl.

Molecular Weight

418.7

Molecular Formula

C₁₆H₁₇Cl₂N₅O₂.HCl

Targets

CDK2/CyclinA: 47 nM; CDK5/p35: 13 nM; AuroraA: >10 μM; c-Abl: >10 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 49 mg/mL (117.03 mM); Warmed water: 40 mg/mL (95.53 mM); Warmed ethanol: 26 mg/mL (62.09 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

AT7519 HCl is used to study its inhibitory activity against multiple CDKs and its effects in cancer therapy.