CDK inhibitor AT7519, Purity ≥98%

Synonym: 844442-38-2; AT-7519; CDK inhibitor

CAS Number: 844442-38-2
Compound CID: 11338033

Product Size

5 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AT7519, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK2/CyclinA, CDK5/p35, AuroraA, and c-Abl.

Molecular Weight

382.2

Molecular Formula

C₁₆H₁₇Cl₂N₅O₂

Targets

CDK2/CyclinA: 47 nM; CDK5/p35: 13 nM; AuroraA: >10 μM; c-Abl: >10 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 9 mg/mL (23.54 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

AT7519 can be used to study its role as a cyclin-dependent kinase (CDK) inhibitor and its effects on inducing apoptosis in cancer cells.