CDK inhibitor AZD5438, Purity ≥98%

Synonym: 602306-29-6; AZD-5438; CDK inhibitor

CAS Number: 602306-29-6
Compound CID: 16747683

Product Size

10 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

MSDS

Properties

Description

AZD5438, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1-cyclin B1, cdk2-cyclin A, cdk2-cyclin E, and cdk4-cyclin D1.

Molecular Weight

371.5

Molecular Formula

C₁₈H₂₁N₅O₂S

Targets

CDK1-cyclin B1: 16 nM; cdk2-cyclin A: 45 nM; cdk2-cyclin E: 6 nM; cdk4-cyclin D1: 449 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 68 mg/mL (183.06 mM); Water: Insoluble; Ethanol: 68 mg/mL (183.06 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

AZD5438 is employed to investigate its inhibition of multiple CDKs and its implications for cancer therapy.