Properties
Description
BMS-265246, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1/CyclinB, CDK2/CyclinE, and CDK4/CyclinD.
Molecular Formula
C18H17F2N3O2
Targets
CDK1/CyclinB: 6 nM; CDK2/CyclinE: 9 nM; CDK4/CyclinD: 230 nM
Solubility
DMSO: 18 mg/mL (52.12 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
BMS-265246 is used to explore its inhibitory activity against CDK1 and CDK2, and its potential applications in cancer research.