Properties
Description
BMS-863233, soluble in DMSO and warmed water and insoluble in ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets Cdc7, CK2, and Pim1.
Molecular Formula
C14H13Cl2N3O2
Targets
Cdc7: 3.4 nM; CK2: 212 nM; Pim1: 42 nM
Solubility
DMSO: Insoluble; Warmed water: 43 mg/mL (131.82 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
BMS-863233 (XL413) can be utilized to investigate the selective inhibition of CDC7 and its impact on DNA synthesis.