CDK inhibitor BS-181 hydrochloride, Purity ≥98%

Synonym: 1397219-81-6; BS181; BS 181; CDK inhibitor

CAS Number: 1397219-81-6
Compound CID: 49867928

Product Size

1 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BS-181 hydrochloride, soluble in DMSO, water and warmed ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1/cycB, CDK2/Cyc E, CDK4/Cyc D1, and CDK5/p35NCK.

Molecular Weight

416.99

Molecular Formula

C₂₂H₃₃ClN₆

Targets

CDK1/cycB: 8.1 μM; CDK2/Cyc E: 0.88 μM; CDK4/Cyc D1: 33 μM; CDK5/p35NCK: 3 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (194.24 mM); Water: 3 mg/mL (7.19 mM); Warmed ethanol: 22 mg/mL (52.75 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

BS-181 hydrochloride is used to research its selective inhibition of CDK7 and its effects on cell cycle progression.