CDK inhibitor, BS-181, Purity ≥98%

Synonym: 1092443-52-1; BS181; 5-N-(6-Aminohexyl)-7-N-benzyl-3-propan-2-ylpyrazolo[1,5-a]pyrimidine-5,7-diamine

MDL: MFCD22056527
CAS Number: 1092443-52-1
Compound CID: 49867929

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BS-181 is an effective cell cycle inhibitor, that has the ability to prevent the pathway of cell cycle by inhibiting CDK. It targets the CDK1/cycB, CDK2/Cyc E, CDK4/Cyc D1, and CDK5/p35NCK.

Molecular Weight

380.53

Molecular Formula

C₂₂H₃₂N₆

Targets

CDK1/cycB: 8.1 μM (IC₅₀); CDK2/Cyc E: 0.88 μM (IC₅₀); CDK4/Cyc D1: 33 μM (IC₅₀); CDK5/p35NCK: 3 μM (IC₅₀)

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Applications

BS-181 is a cell cycle inhibitor that plays a key role in regulating gene expression through its interaction with acetylated lysines on histones.