Properties
Description
CDK2-IN-4, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets Cdk1/cyclin B and cdk2/cyclin A.
Molecular Formula
C23H18N6O2S
Targets
Cdk1/cyclin B: 86 μM; cdk2/cyclin A: 44 nM
Solubility
DMSO: 77 mg/mL (174.01 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
CDK2-IN-4 can be used to explore its selective inhibition of CDK2 and its implications for cell cycle control and cancer.