Properties
Description
CDK8/19-IN-1 is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK19/CycC, CDK8/CycC, and CDK9.
Molecular Formula
C19H18N4O4S2
Targets
CDK19/CycC: 0.99 nM; CDK8/CycC: 0.46 nM; CDK9: 270 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
CDK8/19-IN-1 can be used to investigate the dual inhibition of CDK8 and CDK19 and their role in transcriptional regulation in cancer.