CDK inhibitor CDK8/19-IN-1, Purity ≥98%

Synonym: 1818427-07-4; CDK8/19-IN-1; CHEMBL4066819; 8-[6-(2-methoxyethylcarbamoyl)pyridin-3-yl]oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide; SCHEMBL18429097; CDK inhibitor

CAS Number: 1818427-07-4
Compound CID: 126511854

Product Size

1 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CDK8/19-IN-1 is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK19/CycC, CDK8/CycC, and CDK9.

Molecular Weight

430.5

Molecular Formula

C₁₉H₁₈N₄O₄S₂

Targets

CDK19/CycC: 0.99 nM; CDK8/CycC: 0.46 nM; CDK9: 270 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

CDK8/19-IN-1 can be used to investigate the dual inhibition of CDK8 and CDK19 and their role in transcriptional regulation in cancer.