Properties
Description
CDKI-73, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1, CDK1, CDK2, and CDK2.
Molecular Formula
C15H15FN6O2S2
Targets
CDK1: 8.17 nM; CDK1: 4 nM (Ki); CDK2: 3.27 nM; CDK2: 3 nM (Ki)
Solubility
DMSO: 77 mg/mL (195.2 mM; Water: Insoluble; Ethanol: 1 mg/mL (2.53 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
CDKI-73 is employed to examine its effects as a selective CDK9 inhibitor and its potential as an anti-cancer agent.