CDK inhibitor Centrinone-B, Purity ≥98%

Synonym: 1798871-31-4; LCR-323; LCR323; LCR 323; CDK inhibitor

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Centrinone-B is an CDK kinase inhibitor that disrupts cell division processes. It targets Aurora A, Aurora B, PLK4, and PLK4 (G95L).

Molecular Weight

631.67

Molecular Formula

C₂₇H₂₇F₂N₇O₅S₂

Targets

Aurora A: 1239 nM (Ki); Aurora B: 5597.14 nM (Ki); PLK4: 0.59 nM (Ki); PLK4 (G95L): 497.53 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Centrinone-B is used to investigate its selective inhibition of Centrinone and its effects on centrosome duplication in cell cycle regulation.

Storage

Store at -20ºC.