CDK inhibitor Centrinone, Purity ≥98%

Synonym: 1798871-30-3; LCR-263; LCR 263; LCR263; CDK inhibitor

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Centrinone is an CDK kinase inhibitor that disrupts cell division processes. It targets Aurora A, Aurora B, PLK4, and PLK4 (G95L).

Molecular Weight

633.65

Molecular Formula

C₂₆H₂₅F₂N₇O₆S₂

Targets

Aurora A: 171 nM (Ki); Aurora B: 436.76 nM (Ki); PLK4: 0.16 nM (Ki); PLK4 (G95L): 68.57 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

Centrinone can be used to study its role as a centrin inhibitor and its potential effects on disrupting centrosome function in cancer cells.