Properties
Description
CGP60474 is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1-Cyclin B, cdk2/cyclin A, CDK2/cyclinE, and CDK4/cyclin D.
Molecular Formula
C18H18ClN5O
Targets
CDK1-Cyclin B: 26 nM; cdk2/cyclin A: 4 nM; CDK2/cyclinE: 3 nM; CDK4/cyclin D: 216 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
CGP60474 can be utilized to explore its broad inhibition of CDKs and its potential implications in cancer treatment.