CDK inhibitor CHIR-124, Purity ≥98%

Synonym: 405168-58-3; CHIR124; CDK inhibitor

CAS Number: 405168-58-3
Compound CID: 135399748

Product Size

5 mg; 10 mg; 25 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CHIR-124, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets FLT3, PDGFR, bFGFR, and c-Met.

Molecular Weight

419.9

Molecular Formula

C₂₃H₂₂ClN₅O

Targets

FLT3: 5.8 nM; PDGFR: 6.6 nM; bFGFR: 2.04 μM; c-Met: >3 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 6 mg/mL (14.29 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

CHIR-124 can be used to study its effects as a selective Chk1 inhibitor in cancer research.