CDK inhibitor CVT-313, Purity ≥98%

Synonym: 199986-75-9; CVT 313; NG 26; CVT313; NG26; NG-26; CDK inhibitor

CAS Number: 199986-75-9
Compound CID: 6918386

Product Size

50 mg; 200 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CVT-313, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets Cdk1/cyclin B, cdk2/cyclin A, and Cdk4/cyclin D1.

Molecular Weight

400.47

Molecular Formula

C₂₀H₂₈N₆O₃

Targets

Cdk1/cyclin B: 4.2 μM; cdk2/cyclin A: 0.5 μM; Cdk4/cyclin D1: 215 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 73 mg/mL (182.28 mM); Water: Insoluble; Ethanol: 73 mg/mL (182.28 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

CVT-313 can be employed to study the selective inhibition of CDK2 and its role in cell cycle control.