Properties
Description
Dinaciclib, soluble in warmed DMSO and warmed ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1, CDK2, CDK5, and CDK9.
Molecular Formula
C21H28N6O2
Targets
CDK1: 3 nM; CDK2: 1 nM; CDK5: 1 nM; CDK9: 4 nM
Solubility
Warmed DMSO: 22 mg/mL (55.48 mM); Water: Insoluble; Warmed ethanol: 7 mg/mL (17.65 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Dinaciclib can be used to study its selective inhibition of CDK1, CDK2, CDK5, and CDK9, and its impact on cancer cell proliferation.
