CDK inhibitor Dinaciclib, Purity ≥98%

Synonym: 779353-01-4; SCH727965; SCH-727965; SCH 727965; CDK inhibitor

CAS Number: 779353-01-4
Compound CID: 46926350

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Dinaciclib, soluble in warmed DMSO and warmed ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1, CDK2, CDK5, and CDK9.

Molecular Weight

396.5

Molecular Formula

C₂₁H₂₈N₆O₂

Targets

CDK1: 3 nM; CDK2: 1 nM; CDK5: 1 nM; CDK9: 4 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 22 mg/mL (55.48 mM); Water: Insoluble; Warmed ethanol: 7 mg/mL (17.65 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Dinaciclib can be used to study its selective inhibition of CDK1, CDK2, CDK5, and CDK9, and its impact on cancer cell proliferation.

Storage

Store at -20ºC.