CDK inhibitor Flavopiridol HCl, Purity ≥98%

Synonym: 131740-09-5; Flavopiridol hydrochloride; Alvocidib hydrochloride; Flavopiridol HCl; HL 275; CDK inhibitor

CAS Number: 131740-09-5
Compound CID: 9910986

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Flavopiridol HCl, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1, CDK2, CDK4, and CDK6.

Molecular Weight

438.3

Molecular Formula

C₂₁H₂₀ClNO₅.HCl

Targets

CDK1: 40 nM; CDK2: 40 nM; CDK4: 40 nM; CDK6: 40 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 78 mg/mL (177.96 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Flavopiridol HCl is utilized to study its broad inhibition of CDKs and its effect on inducing cell cycle arrest and apoptosis in cancer cells.

Storage

Store at -20ºC.