Properties
Description
Flavopiridol, soluble in DMSO and ethanol and insoluble in water, is an effective cell cycle inhibitor, that has the ability to prevent the pathway of cell cycle by inhibiting CDK. It targets the CDK1, CDK2, CDK4, and CDK6.
Molecular Formula
C21H20ClNO5
Targets
CDK1: 40 nM; CDK2: 40 nM; CDK4: 40 nM; CDK6: 40 nM
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 14 mg/mL (34.83 mM); Water: insoluble; Ethanol: 7 mg/mL (17.41 mM); In vivo: 5% DMSO + 30% PEG 300 + ddH2O, 2.3 mg/mL
Applications
Flavopiridol is a cell cycle inhibitor that can be used for its anticancer properties.
