CDK inhibitor GDC-0575, Purity ≥98%

Synonym: 1196541-47-5; GDC-0575; GDC 0575; GDC0575; ARRY-575; ARRY-575; ARRY575; RG7741; RG-7741; RG 7741; AK 687476; AK-687476; AK687476; CDK inhibitor

CAS Number: 1196541-47-5
Compound CID: 46917793

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GDC-0575, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes.

Molecular Weight

378.27

Molecular Formula

C₁₆H₂₀BrN₅O

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 68 mg/mL (179.76 mM); Water: Insoluble; Ethanol: 5 mg/mL (13.21 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

GDC-0575 is used to investigate its selective inhibition of CHK1 and its implications for cancer treatment, particularly in combination with DNA-damaging agents.