Properties
Description
GSK461364, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets PLK1.
Molecular Formula
C27H28F3N5O2S
Targets
PLK1: 2.2 nM (Ki)
Solubility
DMSO: 9 mg/mL (16.55 mM); Water: Insoluble; Ethanol: 27 mg/mL (49.66 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
GSK461364 can be used to study its effects as a Plk1 inhibitor in cancer cell proliferation and survival.
