CDK inhibitor GSK461364, Purity ≥98%

Synonym: 929095-18-1; GSK 461364; GSK-461364; CDK inhibitor

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK461364, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets PLK1.

Molecular Weight

543.6

Molecular Formula

C₂₇H₂₈F₃N₅O₂S

Targets

PLK1: 2.2 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 9 mg/mL (16.55 mM); Water: Insoluble; Ethanol: 27 mg/mL (49.66 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

GSK461364 can be used to study its effects as a Plk1 inhibitor in cancer cell proliferation and survival.