Properties
Description
GW843682X is an CDK kinase inhibitor that disrupts cell division processes. It targets Aurora A, CDK2/cyclin A, PDGFR1β, and PLK1.
Molecular Formula
C22H18F3N3O4S
Targets
Aurora A: 4800 nM; CDK2/cyclin A: 7600 nM; PDGFR1β: 160 nM; PLK1: 2.2 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
GW843682X can be used to explore its role as a Plk1 inhibitor in cancer research.