Properties
Description
ICEC0942 HCl, soluble in DMSO, water and ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1, CDK2, CDK4, and CDK5.
Molecular Formula
C22H31ClN6O
Targets
CDK1: 1.8 μM; CDK2: 578 nM; CDK4: 49 μM; CDK5: 9.4 μM
Solubility
DMSO: 76 mg/mL (176.34 mM); Water: 76 mg/mL (176.34 mM); Ethanol: 13 mg/mL (30.16 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
ICEC0942 HCl can be used to investigate its inhibition of CDK7 and its potential therapeutic effects on cancer.