CDK inhibitor Indirubin-5-sulfonate, Purity ≥98%

Synonym: 244021-67-8; Indirubin-5-sulfonate; Indirubin-5-sulphonate; CHEMBL1207227; CHEMBL1208600; CDK inhibitor

CAS Number: 244021-67-8
Compound CID: 3708

Product Size

1 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Indirubin-5-sulfonate is an CDK kinase inhibitor that disrupts cell division processes. It targets Cdk1/cyclin B, cdk2/cyclin A, CDK2/cyclinE, and Cdk4/cyclin D1.

Molecular Weight

342.33

Molecular Formula

C₁₆H₁₀N₂O₅S

Targets

Cdk1/cyclin B: 55 nM; cdk2/cyclin A: 35 nM; CDK2/cyclinE: 150 nM; Cdk4/cyclin D1: 300 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Indirubin-5-sulfonate can be used to investigate kinase inhibition, particularly CDKs, and their roles in cell cycle control.

Storage

Store at -20ºC.