CDK inhibitor K03861, Purity ≥98%

Synonym: 853299-07-7; K 03861; K-03861; CDK inhibitor

CAS Number: 853299-07-7
Compound CID: 11260561

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

K03861, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK2(A144C), CDK2(C118L), CDK2(C118L/A144C), and CDK2(WT).

Molecular Weight

501.5

Molecular Formula

C₂₄H₂₆F₃N₇O₂

Targets

CDK2(A144C): 15.4 nM (Kd); CDK2(C118L): 18.6 nM (Kd); CDK2(C118L/A144C): 9.7 nM (Kd); CDK2(WT): 50 nM(Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 97 mg/mL (193.42 mM); Water: Insoluble; Ethanol: 15 mg/mL (29.91 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

K03861 can be used to study the inhibition of CDKs and its potential therapeutic applications in cancer research.