Properties
Description
Lerociclib dihydrochloride is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1/cyclinB1, cdk2/cyclin A, CDK2/cyclinE, and Cdk4/cyclin D1.
Molecular Formula
C26H36Cl2N8O
Targets
CDK1/cyclinB1: 2.4 μM; cdk2/cyclin A: 1.5 μM; CDK2/cyclinE: 3.6 μM; Cdk4/cyclin D1: 1 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
Lerociclib dihydrochloride can be used to investigate its effects as a selective CDK4/6 inhibitor in cell cycle control.