CDK inhibitor Lerociclib, Purity ≥98%

Synonym: 1628256-23-4; G1T-38; G1 T38; G1T38; CDK inhibitor

CAS Number: 1628256-23-4
Compound CID: 86269224

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Lerociclib, soluble in DMSO and insoluble in ethanol and water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1/cyclinB1, cdk2/cyclin A, CDK2/cyclinE, and Cdk4/cyclin D1.

Molecular Weight

474.613

Molecular Formula

C₂₆H₃₄N₈O

Targets

CDK1/cyclinB1: 2.4 μM; cdk2/cyclin A: 1.5 μM; CDK2/cyclinE: 3.6 μM; Cdk4/cyclin D1: 1 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 2 mg/mL (4.21 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Lerociclib can be used to investigate its selective inhibition of CDK4/6 and potential for treating advanced breast cancer.