Properties
Description
MC180295, soluble in DMSO and water and insoluble in ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1-Cyclin B, cdk2-cyclin A, cdk2-cyclin E, and CDK3-Cyclin E.
Molecular Formula
C17H18N4O3S
Targets
CDK1-Cyclin B: 138 nM; cdk2-cyclin A: 233 nM; cdk2-cyclin E: 367 nM; CDK3-Cyclin E: 399 nM
Solubility
DMSO: 64 mg/mL (178.56 mM); Water: 64 mg/mL (178.56 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
MC180295 can be used to investigate its role as a selective CDK9 inhibitor affecting transcription regulation.
