CDK inhibitor MC180295, Purity ≥98%

Synonym: 2237942-08-2; MC180295; MC-180295; MC 180295; CDK inhibitor

CAS Number: 2237942-08-2
Compound CID: 137333456

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MC180295, soluble in DMSO and water and insoluble in ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1-Cyclin B, cdk2-cyclin A, cdk2-cyclin E, and CDK3-Cyclin E.

Molecular Weight

358.41

Molecular Formula

C₁₇H₁₈N₄O₃S

Targets

CDK1-Cyclin B: 138 nM; cdk2-cyclin A: 233 nM; cdk2-cyclin E: 367 nM; CDK3-Cyclin E: 399 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 64 mg/mL (178.56 mM); Water: 64 mg/mL (178.56 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

MC180295 can be used to investigate its role as a selective CDK9 inhibitor affecting transcription regulation.