Properties
Description
NG52, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets cdc2-cyclin B, Cdc28p, Pho85p, and phosphoglycerate kinase 1 (PGK1).
Molecular Formula
C16H19ClN6O
Targets
cdc2-cyclin B: 0.34 μM; Cdc28p: 7 μM; Pho85p: 2 nM; Phosphoglycerate kinase 1 (PGK1): 2.5 μM
Solubility
DMSO: 59 mg/mL (170.12 mM); Water: Insoluble; Ethanol: 20 mg/mL (57.66 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
NG52 can be utilized in research focusing on the modulation of signal transduction pathways.
