Properties
Description
NG52, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets cdc2-cyclin B, Cdc28p, Pho85p, and phosphoglycerate kinase 1 (PGK1).
Molecular Formula
C16H19ClN6O
Targets
cdc2-cyclin B: 0.34 μM; Cdc28p: 7 μM; Pho85p: 2 nM; Phosphoglycerate kinase 1 (PGK1): 2.5 μM
Solubility
DMSO: 59 mg/mL (170.12 mM); Water: Insoluble; Ethanol: 20 mg/mL (57.66 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
NG52 can be utilized in research focusing on the modulation of signal transduction pathways.