CDK inhibitor NU6027, Purity ≥98%

Synonym: 220036-08-8; NU-6027; NU 6027; CDK inhibitor

CAS Number: 220036-08-8
Compound CID: 398148

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

NU6027, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets ATR, CDK1, CDK2, and DNA-PK.

Molecular Weight

251.28

Molecular Formula

C₁₁H₁₇N₅O₂

Targets

ATR: 0.4 μM (Ki); CDK1: 2.5 μM (Ki); CDK2: 1.3 μM (Ki); DNA-PK: 2.2 μM (Ki)

Form

Lyophilized powder

Purity

Solubility

DMSO: 47 mg/mL (187.04 mM); Water: Insoluble; Ethanol: 3 mg/mL (11.93 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

NU6027 can be employed to investigate the inhibition of CDK2 and its implications for cancer therapy.