Properties
Description
NU6027, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets ATR, CDK1, CDK2, and DNA-PK.
Molecular Formula
C11H17N5O2
Targets
ATR: 0.4 μM (Ki); CDK1: 2.5 μM (Ki); CDK2: 1.3 μM (Ki); DNA-PK: 2.2 μM (Ki)
Solubility
DMSO: 47 mg/mL (187.04 mM); Water: Insoluble; Ethanol: 3 mg/mL (11.93 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
NU6027 can be employed to investigate the inhibition of CDK2 and its implications for cancer therapy.
